CACNA1F

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CACNA1F

A gene on chromosome Xp11.23 that encodes the alpha-1F subunit of a voltage-dependent calcium channel, which mediates the entry of calcium ions into excitable cells. These channels are also involved in various calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and apoptosis. CACNA1F gives rise to long-lasting (L-type) calcium channels that belong to the high-voltage activated (HVA) group; they are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines and by omega-agatoxin-IIIA.

Molecular pathology
Defects in CACNA1F cause Aaland Island eye disease, cone-rod dystrophy X-linked type 3, and congenital stationary night blindness type 2A.
References in periodicals archive ?
Personally, I always preferred playing COD4 on Hardcore setting, as the damage inflicted by the weapons was more realistic.
And, of course, all the pistols--Beretta M9, HK USP .45, M1911, and the ubiquitous "Deagle", the Desert Eagle, all just in the original COD4.
Caption: Here's one of the many mulitiplayer maps available for COD4, "Overgrown".
World At War has its moments, but for anyone who has played COD4, the two games are miles apart.
Whereas COD4 featured a constant corralling of your direction, all too often this is ignored and fails to mask the game's linearity, which detracts from its life.
These 20-odd challenges,which become unlocked as the campaign develops, are a fantastic sub-plot -offering tricky tasks similar to the epilogue mission in the original CoD4.