It has been reported that plant extract containing alkaloids, flavonoids, tannin, and terpenoids possesses CNS depressant
Two classes of CNS depressants
have the potential for misuse, abuse, and addiction: benzodiazepines and barbiturates.
The metabolism to morphine by CYP2D6 is responsible for most of the analgesic and CNS depressant
effects of codeine.
For example, when cough syrup containing the CNS depressant
dextromethorphan (DXM) is abused or mixed with other drugs, the syrup can contribute to car accidents when the abuser is slow or unable to react.
Despite the CNS depressant
activity of GHB, several subjects reported enhanced sensory experiences, such as vision, hearing, and touch.
Keywords: Cymbopogon winterianus; CNS depressant
; Anticonvulsant activity; Pentylenetetrazol; Picrotoxin; Strychnine
It also lacks the generalized CNS depressant
effects characteristic of traditional sedative-hypnotics, making it an attractive agent for treating insomnia in patients with chronic obstructive pulmonary disease (COPD), according to studies presented at the meeting.
The bisepoxylignan glycoside simplexoside has CNS depressant
activity in mice and rats while the aglycone is a stimulant (Ghosal et al., 1980).
inflata has CNS depressant
properties, manifested as antinociception and sedation.
GHB is a powerful CNS depressant
that appears to work by improving nighttime sleep.