CNR1


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CNR1

A gene on chromosome 6q14-q15 that encodes one of two cannabinoid receptors, which belong to the G protein-coupled receptor family. CNR1 inhibits adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner, and is responsible for cannabinoid-induced CNS effects (e.g., effects on mood and cognition) of marijuana. CNR1 is also a less preferred gene symbol for what is now designated as PCDHA4, see there.
References in periodicals archive ?
CNR1 variation modulates risk for drug and alcohol dependence.
Melamede states, "Cannabis Science is very appreciative of the opportunity to present the clinical premise supporting the development of CS-TATI-1 to address the application of CNR1 and CNR2 agonists and antagonists of HIV Tat expression inhibitors to legislative staffers of ranking Members of Congress directly preceding the opening of the XIX International AIDS Conference," said Dr.
It's a very important for the further development of CS-TATI-1 to provoke legislative interest in CS-TATI-1 to ensure federal facilitation of further development of the clinical advancement of research necessary for the commercialization of CNR1 and CNR2 agonists and antagonists of HIV Tat expression inhibitors," said Mariel Selbovitz, MPH.