ABCC2

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ABCC2

A gene on chromosome 10q24 that encodes a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes, many of which are involved in multidrug resistance. ABCC2 is found in the canalicular (apical) part of hepatocytes and involved in biliary transport. Its substrates include chemotherapeutics (e.g., vinblastine) and thus contributes to drug resistance in humans.
 
Molecular pathology
ABCC2 is mutated in patients with Dubin-Johnson syndrome.
References in periodicals archive ?
The CMRP is one of three projects funded by the Port Improvement Rate (PIR), a temporary levy charged on vessels entering and exiting the harbour which funds capital improvements to sustain and improve the safe long-term operation of the Port.
Para determinar la existencia de diferencias significativas entre los distintos grupos, se realizo un analisis comparativo de las frecuencias, utilizando el estadistico chi cuadrado para cada uno de los items del CMRP.
La dimension psicosocial estaba compuesta por ocho items en el CMRP. De ellos, un unico item--sexo deseado del bebe--obtuvo un valor de significatividad en chi cuadrado [[ji al cuadrado] (6) = 15.283, p < 0.05].
De maneira geral, as medidas de tendencia central, de variabilidade, de assimetria e curtose e o teste de Lilliefors, em relacao aos caracteres morfologicos: altura de planta (AP), numero de racemos por planta (NRP) e comprimento medio dos racemos por planta (CMRP), e aos produtivos: numero de frutos por planta (NFP), numero de frutos por racemo (NFR) e produtividade de graos (PROD), revelaram boa aderencia dos dados, das 75 plantas de crambe (Crambe abyssinica Hochst), a distribuicao normal (Tabela 1).
Caso a opcao seja amostrar 75 plantas, o erro de estimacao seria de [+ or -] 4,49, [+ or -] 5,75, [+ or -] 6,17, [+ or -] 14,33, [+ or -] 10,60 e [+ or -] 14,26% da estimativa da media (m), respectivamente, para os caracteres AP, NRP, CMRP, NFP, NFR e PROD.
El CMRP se aplico, de manera anonima, individual y voluntaria, a madres biologicas pertenecientes a las distintas asociaciones de autismo de Galicia.
Al mismo tiempo, se realizo una comparativa de las frecuencias, mediante chi-cuadrado ([ji al cuadrado]), aplicada la correccion de Yates debido a los reducidos tamanos muestrales de las frecuencias esperadas, de los grupos estudiados en cada uno de los items del CMRP.
Matt Spurlock (CLS, CMRP, CRL) of Advanced Machine Reliability Resources, Inc.
Additionally, Eric is Six Sigma trained and is a Certified Maintenance and Reliability Professional (CMRP).
Ahmed is a joint post-doctoral fellow in Human Health at ANSTO and the Centre for Medical Radiation Physics (CMRP) at UOW and his research focuses on modelling of positron emission tomography (PET) systems and developing image reconstruction algorithms.
Tenders are invited for Overhauling Servicing Testing And Re Commissioning Of Marp And Cmrp System Of Unit No 12Th Btps Obra
Address : Numro national d~identification : 26490025900039, 20 RUE TUBOEUF BP 100 16, 49170, Saint Georges sur Loire, F, Courriel : service-3 cmrp.org , Code NUTS : FR512