CDK4

(redirected from CMM3)

CDK4

A gene on chromosome 12q14 that encodes a Ser/Thr kinase, which is the catalytic subunit of the cyclin-dependent protein kinase complex. CDK2 activity is restricted to the G1-S phase, and is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a).

Molecular pathology
CDK4 mutations and those of related proteins (e.g., D-type cyclins, p16(INK4a) and Rb) occur in neoplasia.
References in periodicals archive ?
of questions Factor type loading w Hedonic HMl .95 [alpha] = .96 motivation HM2 .94 CR = .96 HM3 .93 AVE = .88 Utilitarian UM1 .96 [alpha] = .93 motivation UM2 .98 CR = .93 UM3 .77 AVE = .82 Compliance CMM1 .97 [alpha] = .96 motivation CMM2 .98 CR = .96 CMM3 .90 AVE = .90 Conformity CNM1 .95 [alpha] = .95 motivation CNM2 .90 CR = .95 CNM3 .93 AVE = .86 Affiliation AMI .87 [alpha] = .91 motivation AM2 .88 CR = .91 AM3 .88 AVE = .77 Construct No.