IL12A

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IL12A

A gene on chromosome 3p12-q13.2 that encodes interleukin-12A, a cytokine which acts on T and natural killer cells and has a broad array of biological activities; it is required for the T-cell-independent induction of interferon-gamma, and is important for Th1 and Th2 cell differentiation. IL12A acts as a growth factor for activated T and NK cells and enhances the lytic activity of NK/lymphokine-activated killer cells.
References in periodicals archive ?
The lowest results are consistently obtained when using the CLMF approach, which consists in using only the most frequent translation from the cluster chosen through the WSD procedure.
"A programme of one off special events booked to coincide with CLMF will also be announced.
(Nutley, NJ) has patented a novel cytokine protein called IL-12 or Cytotoxic Lymphocyte Maturation Factor (CLMF) produced and synthesized by human NC-37 B lymphoblastoid cells.