PDLIM1

(redirected from CLIM1)

PDLIM1

A gene on chromosome 10q23.1 that encodes a cytoskeletal protein that may serve as an adapter to recruit other proteins (e.g., kinases) to a particular site in the cytoskeleton.
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Category/name Function Change (x-fold) Cellular defense HSP27 Protein stabilisation + + Apoptosis/degeneration Cathepsin Z Lysosomal proteolysis + + Proliferation Annexin Growth factor + + Migration Cofilin Actin turnover +++ Tropomodulin 3 Actin turnover ++++++ CLIM1 Actin kinase ++++++ adaptor Galectin Cell to cell ++ interaction [beta]-Hexosaminidase Glycosidasis ++++++ [beta]-subunit Metabolism Pyruvate kinase 3 Glycolysis - Enolase 1 Glycolysis - Nuclear transport Ran-binding protein 1 RanGAP activity + + elF5A Cofactor in ++++++ nuclear export Translation CRHSP-24 Translation ++++++ regulating protein Adapted from Zuidervaart et al.