CLEC6A

CLEC6A

A gene on chromosome 12p13 that encodes a C-type lectin domain protein involved in Ca2+-dependent binding of high-mannose carbohydrates present on the surface of Candida albicans, dust mites and Schistosoma mansoni eggs, altering the adaptive immune response.
References in periodicals archive ?
The binding of mycobacterial PAMPs to their receptors, CLEC7A, CLEC6A, or CLEC4E, stimulates Syk activation in their signal transduction [71], and Syk knock-out mice show attenuated antibacterial host defense [72].
Dectin-2 (or DCAL-2, Clec6A) or beta-glucan receptor is a C-type lectin receptor expressed on DCs, macrophages, neutrophils, and monocytes (Table 1) [170].
DCAL-2 Expressed on DCs, macrophages neutrophils, Dectin-2 Clec6A and monocytes.