AP1B1(redirected from CLAPB22 3 5)
AP1B1A gene on chromosome 22q12.2 that encodes a large subunit of the heterotetrameric, trans-Golgi, clathrin-associated adaptor-related protein complex AP-1, which is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. The vesicles are involved in endocytosis and Golgi processing. The AP complexes recruit clathrin to membranes and recognise sorting signals within the cytosolic tails of transmembrane cargo molecules.
AP1B1 is a candidate meningioma gene.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.