Only variable reactivity has been seen with CK7, CK8
, CK18, and CK19.
Concurrently, in vivo exposure to EE, 25, and 250 [micro]g BPA/kg-BW significantly suppressed luminal progenitor markers (determined by alignment with CK8
) (Figure 3B).
The immunohistochemical stains gave positive results for cytokeratin 7 (CK7), cytokeratin 8 (CK8
), estrogen receptor (ER) (strong, 99%), progesterone receptor (PR) (strong, 99%) (Figure 5), Smad4 (DPC4), GAtA binding protein 3 (GATA-3), gross cystic disease fluid protein 15 (GCDFP-15), and mammaglobin (Figure 6).
Immunohistochemistry showed that those carcinoma cells were specifically positive for not only CK7 (Figure 1(f)) but also CK18 (Figure 1(f)) and c-kit (potential stem cells marker) [3, 5], whereas they were negative for CK8
, Hepatocyte, and CD56.
The observed groundwater levels are from some wells including CK7 and CK8
. And the measured solute concentrations are from well CK8
In the poorly-differentiated case of SCC, CK1 and CK10 were not expressed, but simple epithelial keratins (CK8
, 18, and 19) were expressed.
Only four of the Food and Drug Administration (FDA)-approved markers (CA 15-3, CA 27.29, HER- 2/neu, and circulating tumor cells analysis of EpCAM, CD45, CK8
, 18, 19) can be measured and assessed longitudinally.
The lining epithelia exhibited a negative expression pattern for CK8
The tumor cells were positive for HMB45, SMA, Melan-A (A103), vimentin and negative for CD117, CK7, CK8
, CD10, and RCC.
AE1/AE3, Cam5.2) and low-molecular weight cytokeratins (CK7, CK8
The stains showed diffuse +AFP, Glipan, and CK8
; +Heppar in the solid areas; +CK17 and 19 in the glandular areas; -chromogranin, CD20, ER, PR, and GCDFP15; +luminal/focal polygonal CEA (Figures 2(a) and 2(b)).