CK7

CK7

This is a popular (non-HUGO) symbol for what is now designated KRT7, see there. CK7 is so widely used among pathologists that it is unlikely to disappear from the working medical parlance.
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The lining of the cyst was attenuated and highlighted by creatinine and CK7 stains.
Both lesions were positive for CA19-9, CEA, CK20, and CK7 immunohistochemical stains.
Immunohistochemical studies were undertaken using antibodies CK7 (1:750 Dako), cytokeratin AE1/AE3 (1:1000 Dako), EMA (1:750 Dako), CD10 (1:300 Novocastra), vimentin (1:4000 Dako), S100 (1:4000 Dako), TTF-1 (1:250 Novocastra) and thyroglobulin (1:500 Dako).
There was no staining for AE1 AE3, pancytokeratin, H-caldesmon, myogenin, CK 5/6, CK14, p63, 34BE12, CD34, CK7, CD56, EMA, S100, melan A, c-KIT and CD99.
11) CK7 staining may be strongly positive, whereas CK20 staining is usually negative.
CK7 CK2O Pan keratin CD45 S100 TTF1 Melanoma - - - - + - NHL - - - + - - Breast carcinoma + - + - - - Bronchogenic carcinoma + - + - - + Gastric carcinoma + + + - - - Renal cell carcinoma - - + - - - Nasopharyngeal - - + - +/- - carcinoma
The neoplastic cells show strong and well-developed positive reactions with thyroglobulin, TTF-1, keratin, and CK7.
Adenokarsinom grubunda 12 olgudan 8'inde TTF-1 calisilmis olup bunlarin 7'inde (%87) pozitiflik izlenmistir, negatif olan bir olguda ise CK7 pozitifligi mevcuttur.
Briefly, reactions were performed with a probe concentration of 200 nmol/L and a 60-s anneal/extend phase at 60 [degrees]C for GUSB, [5] CK19, CK20, EGFR, MGB1, PTHrP, SCCA, and SFTPB; 62 [degrees]C for CK7, MAGEA-plex, MART1, and MGB2; and 64 [degrees]C for CEA, LUNX, PIP, TACSTD1, TM4SF3, and TYR.
2) and were immunohis-tochemically positive for CK20 and negative for CK7, supporting their colorectal origin.
This biopsy was consistent with the prior biopsy, staining positive for CK7, ER (40%), BRST-2/GCDFP-15, and GATA-3.