KRT10

(redirected from CK10)

KRT10

A gene on chromosome 17q21 that encodes a type-I (acidic) member of the cytokeratin family, which belongs to the superfamily of intermediate filaments, that with actin microfilaments and microtubules forms the epithelial cell cytoskeleton.

Molecular pathology
KRT10 mutations cause epidermolytic hyperkeratosis.
References in periodicals archive ?
In a case series of four tumors, the authors reported intense and diffuse positivity for CK7, variable expression of epithelial membrane antigen (EMA), vimentin, S100, Ulex europaeus antigen, high-molecular weight CK, CK 8, CK 18 and CK19, and diffuse negativity for carcinoembryonic antigen (CEA), CD15, CD34, desmin, actin, CK10, CK20 and HMB45 [15].
El grupo 4 es claramente el perfil de los sitios Llolleo del sureste de Colonia Kennedy y Peuco (CK1/6, CK10, CK11, EP) y el grupo 5 de los sitios de mas al norte cercanos al estero La Berlina, tanto Bato como Llolleo (CK2, CK3, CK4).
Las muestras de Angostura, cercanas al sitio El Peuco (EP), las de Lomas del Aguila, cercanas a los sitios CK10 y CK11 y la de Las Tazas, cercanas a los sitios de Valdivia de Paine, no tienen probabilidad estadistica de ser parte de ningun grupo quimico de las muestras de ceramica analizadas.
The monoclonal antibody 34[beta]12 targets cytoplasmic highmolecular-weight cytokeratin filaments in basal cells of the benign prostatic glands, namely CK1, CK5, CK10, and CK14.
In areas of squamous metaplasia seen in both squamous cell carcinoma and mucoepidermoid carcinoma, SCC is positive for CK10 and MEC for CK13.
In all samples, the score for CK10 was 3, which implied a housekeeping function that potentially can be used for sample normalization.
Antibodies to a number of basal-type and highmolecular-weight cytokeratins, including cytokeratin (CK) 1, CK5, CK5/6, CK10, CK14, and CK17, react variably with breast MECs.
The antibody 34pE12 identifies a cocktail of acidic and basic CK, including CK1, CK5, CK10, and CK14.