KRT4

(redirected from CK-4)

KRT4

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin that is specifically co-expressed in differentiated layers of mucosal and oesophageal epithelia with family member KRT13.

Molecular pathology
KRT4 mutations are associated with white sponge nevus, which is characterised by oral, oesophageal and anal leukoplakia.
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A full synthetic oil, the new T6 Multi-Vehicle 5W-30 meets the API CK-4 specification for diesel engines and API SN specification for gasoline engines.
Rotella T6 Multi-Vehicle 5W-30 has been extensively evaluated, Shell Lubricants engineers note, and exhibits excellent performance across API CK-4 and OEM tests, plus outstanding wear, oxidation and deposit control for diesel engines.
Next month will see the introduction of API CK-4 and API FA-4--a development that represents the biggest industry overhaul in heavy-duty engine oil specifications for decades.
API CK-4 licensed oils will offer backward compatibility, allowing use in the vast majority of older diesel engine vehicles that ran previous oil categories (CJ-4, CI-4 Plus, CI-4, etc.) while offering increased performance and protection gains.
New Shell Rotella T4 Triple Protection 15W-40 and 10W-30 along with Shell Rotella T5 Synthetic Blend 10W-30 are formulated to meet the specification criteria for the new API CK-4 service category for diesel engine oil.
"We have been working on the new CK-4 and FA-4 specifications of heavy duty engine oils for more than five years, keeping in mind that meeting the new specifications was simply a starting point for Shell Rotella," said Chris Guerrero, global heavy-duty diesel engine oil brand marketing manager.
Premiering in December, API Service Categories CK-4 and FA-4 succeed Service Category CJ-4 oils that have been widely recommended among on- and off-highway diesel engine manufacturers over the past decade.