CJD


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CJD

Abbreviation for Creutzfeldt-Jakob disease.

CJD

abbr.
Creutzfeldt-Jakob disease

PRNP

A gene on chromosome 20p13 that encodes a membrane glycosyl-phosphatidylinositol-anchored glycoprotein, which aggregates into rod-like structures and contains a highly unstable region of five tandem octapeptide repeats. The exact function of PrP is unknown.

Molecular pathology
PRNP mutations are linked to Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington-like disease 1 and kuru.

CJD

Creutzfeldt-Jakob disease, see there.

CJD

Abbreviation for Creutzfeldt-Jakob disease.

CJD

Abbreviation for Creutzfeldt-Jakob disease.

Patient discussion about CJD

Q. Recently i heard about Creutzfeldt-Jakob disease Recently i heard about Creutzfeldt-Jakob disease. I like to know (To ask the Secretary of State for Health), how many people under the age of 20 years in each of the last five years have suffered from Creutzfeldt-Jakob disease; and of these how many had not had any growth treatment previously? How serious is it?

A. i found some statistics about what you wanted, but it's only until 1994 :(
http://www.cdc.gov/ncidod/eid/vol2no4/holman2.htm

but it's very elaborated and might give you a clue..

More discussions about CJD
References in periodicals archive ?
Often, the most difficult aspect of CJD is making the diagnosis.
The disease leapt into public awareness decades ago when people in Britain were diagnosed with a type of CJD after eating meat from diseased cattle.
Brain MRI showed subtle diffusion restriction in bilateral caudate and lentiform nucleus on DWI (Figure-3), consistent with early CJD. It also showed abnormal foci in bilateral periventricular and subcortical white matter on FLAIR MRI images, suggestive of microangiopathy.
Notification and support for people exposed to the risk of Creutzfeldt--Jakob disease (CJD) (or other prion diseases) through medical treatment (iatrogenically) The Cochrane Collaboration.
Moreover, since many radiology reports miss the pathognomonic MRI findings of CJD, "it is critical that physicians be aware of MRI findings in prion disease and read their patients' MRIs [themselves]," Dr.
However, it is possible that the proteins which cause CJD, known as prions, survived these routine sterilisation procedures so an extremely small risk of transmission remains."
The team tested cerebrospinal fluid samples from 18 people with CJD and 35 people with other neurodegenerative diseases.
"Dadwas such an intelligent, kind, energeticman and to see what CJD did to someone you love was heartbreaking," said Catherine, from Longdon, Staffordshire.
A search of electronic databases Medline (1950 to November 2008), Embase and Evidence Based Medicine Reviews using keywords "CJD", "anaesthesia" (MeSH terms) and "New Zealand" (key word) was performed to source relevant articles.
During 1996-2008, as clinicians reported additional CJD cases to the surveillance system sponsored by the Ministry of Health and Welfare, the number of persons identified with CJD associated with cadaveric dura mater grafts increased from 43 initially to 132.
"Until we develop a rapid screening test, the unknowing carriers pose a great risk of infecting others." Prof Ironside was a member of the National CJD Surveillance Unit that identified variant CJD in 1996.
Through genetic analysis, researchers were able to identify 15 CJD patients with the E200K genetic mutation on chromosome 20, 20 healthy carriers of the E200K mutation (the premorbid group) who are at high risk of developing CJD, and 20 healthy members of the same family who do not have the mutation and will not develop the disease (healthy controls).