SOCS1

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SOCS1

A gene on chromosome 16p13.13 that encodes a member of the suppressor of cytokine-signalling—i.e., STAT-induced STAT inhibitor—family, which are cytokine-inducible negative regulators of cytokine signalling. SOCS1 expression is induced by cytokines (e.g., IL2, IL3, erythropoietin, CSF2/GM-CSF and interferon-gamma), and it provides a negative feedback loop to attenuate cytokine signalling.
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where 2.48, 2.86, 2.56, 3.78, and 5.79 eV of the thermal reaction energies at 298.15 K and 1 atm are absorbed for 1,16-dimethyl derivative (trans-1, [D.sub.3d]), 1,7-dimethyl derivative (equatorial, [C.sub.2]), 1,6-dimethyl derivative (trans-2, [C.sub.2v]), 1,4-dimethyl derivative (cis-2, [C.sub.s]), and 1,2-dimethyl derivative (cis1, [C.sub.2v]), respectively.
Ohyashiki, "Thrombopoietin induces an SH2-containing protein, CIS1, which binds to MP1: involvement of the ubiquitin proteosome pathway," Experimental Hematology, vol.
The presence of cis1,4-polybutadiene is specifically indicated by the diagnostic band at 733 cm-1 along with the band at 3010 [cm.sup.-1].