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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
BB x bulls to PS373, av PS242.41; BB x hfrs to PS282, av PS140.73; Sim x bulls to PS365, av PS231.75; Sim x hfrs to PS270, av PS160.16; Lim x bulls to PS305, av PS196.22; Lim x hfrs to PS332, av PS201.67; Char x bulls to PS350; Char x hfrs to PS235, av PS156.67; AA x bulls to PS235, av PS110.20; AA x hfrs to PS145, av PS65.21; Hfd x bulls to PS170, av PS123.08; Hfd x hfrs to PS155, av PS112.78; B&W bulls to PS138, av PS53.01.
The corresponding amount of biomass char required for 1 kg iron ore concentrate, blend ratio of biomass char and carbon content in pellets could be calculated based on the mass balance of carbon and oxygen elements.
Using 20, 30, 40, 70 mesh sieve to screen out 20~30 mesh, 30~40 mesh, 40~70 mesh coal sample; Coal sample is roasted for the preparation of pyrolysis char in the case of anaerobic.
Overall, the agreement between the computed and experimental values is satisfactory but the equation fails to predict the experimental results for C[O.sub.2] loading less than about 0.32 mmol/g of char from which the adsorption takes place in very small pores.
The Char Mausum offers a takeaway service for those who prefer to eat at home.
To elucidate how the formation of chars affected the combustion of the flame-retardant PP composites, the residue left at 600[degrees] C after 5 min in muffle furnace are examined for change in char appearance with the aid of a camera.
Recent research has shown that inorganic fillers, such as Ti[O.sub.2] (16) and molybdenum disilicide, (17) could react with APP or phosphoric acid and form a ceramic material with a high heat-resistance covering on the surface of the char layer.
Spawning and overwintering habitats used by Arctic char are often in the same locations since they have similar characteristics (DFO, 2004).
The char, which weighed about a pound, was spotted by angler John Robertson in the lade near Stormontfield.
Under high temperature, polyurethane foam can produce char particles formed from dehydrogenation and particles of compounds containing a small number of hydrogen atoms.
The pyrolysis product is a solid having low volatile matter and high fixed carbon content, which is called char. After char formation, the solid residue is burned at a burning rate affecting the combustion equipment design.