acetaldehyde

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acetaldehyde

 [as″et-al´de-hīd]
a colorless volatile liquid used in the manufacture of acetic acid, perfumes, and flavors, which is irritating to mucous membranes and has a general narcotic action. It is also an intermediate in the metabolism of alcohol.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ac·et·al·de·hyde

(as-e-tal'dĕ-hīd),
An intermediate in yeast fermentation of carbohydrate and in alcohol metabolism. It is a central agent for the toxic effects of ethanol.
Synonym(s): acetic aldehyde, ethanal
Farlex Partner Medical Dictionary © Farlex 2012

acetaldehyde

(ăs′ĭ-tăl′də-hīd′)
n.
A colorless, flammable liquid, C2H4O, used to manufacture acetic acid, perfumes, and drugs.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

acetaldehyde

The major metabolic product of ethanol, which is generated by ethanol dehydrogenase and subsequently metabolised to acetate by aldehyde dehydrogenase. It is responsible for alcohol’s toxic effects.

It is postulated that the liver injury induced by ethanol is due to tissue responses to acetaldehyde, including acetaldehyde-induced fibrogenesis, acetaldehyde-induced lipid peroxidation enzyme inhibition, and formation of antibodies against acetaldehyde adduct proteins—e.g., serum albumin, hemoglobin, and cytokskeletal proteins, including tubulin.

Ref range
< 0.02 mg/dL.
 
Method
Gas chromatography.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

acetaldehyde

Toxicology The major metabolic product of ethanol, which is generated by ethanol dehydrogenase and subsequently metabolized to acetate by aldehyde dehydrogenase, and responsible for drinking-alcohol's toxic effects
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ac·et·al·de·hyde

(as'ĕ-tal'dĕ-hīd)
An intermediary product in the metabolism of alcohol.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

acetaldehyde

A product of the metabolism of large amounts of alcohol. The reaction is catalyzed in the liver by the enzyme alcohol dehydrogenase. The principal cause of the toxic effects of strong drink. Acetaldehyde is a powerful poison, considerably more toxic than alcohol, and is capable of damaging almost any part of the body. Fortunately the body has a range of detoxifying enzymes, aldehyde dehydrogenases, one of which, ALDH2, rapidly break down the acetaldehyde molecule.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005