cGMP


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guanosine

 [gwah´no-sēn]
a nucleoside, guanine riboside, one of the major constituents of RNA.
cyclic guanosine monophosphate a cyclic nucleotide, guanosine 3′,5′-cyclic monophosphate, an intracellular “second messenger” similar in action to cyclic adenosine monophosphate; the two cyclic nucleotides activate different protein kinases and usually produce opposite effects on cell function. Abbreviated 3′,5′-GMP, cGMP, and cyclic GMP.
guanosine monophosphate (GMP) a nucleotide important in metabolism and RNA synthesis.
guanosine triphosphate (GTP) a nucleotide required for RNA synthesis and involved in energy metabolism.

cGMP

cGMP

abbr.
cyclic GMP
References in periodicals archive ?
Also of significance is the fact that Pharmaceutical cGMP requirement 211.94 (drug product containers and closures) is addressed in the Medical Device cGMP mandate 820.30 (design controls).
I also find it interesting that Design Change is not included in the medical device cGMP regulation.
Effect of Ang-(1-7) on cGMP Phosphodiesterase in Corpus Cavernosum of Control and Diabetic Rats.
Packaging & labeling control requirements; Records & Report requirements under FDA CGMPs.
Soltero created InstantGMP[TM] INV because he discovered a market need for a cloud-based cGMP software system, but through experience realized that the move to complete electronic batch records can be cumbersome for many companies.
To help the industry understand the benefits and limitations of botanical, macroscopic and organoleptic analysis of herbal ingredients for cGMP compliance, the American Herbal Products Association (AHPA) is partnering with the American Herbal Pharmacopeia (AHP) to present a two-day, hands-on workshop at Portland State University in Oregon on June 15-16.
In turn, NO elevates the levels of cGMP (Snyder & Bredt, 1991).
The current-voltage (I-V) relationship of the cGMP conductance in amphibian rods displays large outward rectification [15, 16], very well fitted by an exponential function with a voltage constant between +10 and +15 mV [15].
The second messenger cyclic GMP (cGMP) is a signaling molecule whose levels are regulated by an equilibrium between its production and removal.
FDA's cGMP regulations for drugs establish minimum standards for cGMP compliance.
Albemarle Corporation (NYSE: ALB), a global developer, manufacturer and marketer of highly engineered specialty chemicals and services, has expanded the kilo lab at its FDA-registered cGMP active pharmaceutical ingredient production facility in South Haven, Michigan.
Forty-nine selections are arranged according to broad theme, including downstream recovery of cells and protein capture, process development in downstream purification, equipment design for protein purification, cGMP operations, biopharmaceutical facility validation, and FDA CGMP regulatory compliance.