The patients' marrow is then processed through two types of AIS CELLector devices that collect and selectively isolate the patients' CD34 stem cells, the precursors of white and red blood cells.
The cells were not found to be contaminated by any biologicals such as monoclonal antibodies, which allows safe repeated infusions of cells processed by AIS CELLectors, and offers the possibility of greater safety to the patient.
an affiliate of Baxter Healthcare Corporation, announced today the formation of AIS/Caremark Cell Therapy, a joint venture to develop and operate ex vivo cell therapy centers using the AIS CELLector
(TM) for treatment of HIV positive and AIDS patients.
The trial evaluates the safety and effectiveness of the AIS CELLector
device set for purging T and B cells from allegeneic bone marrow in matched related bone marrow transplant patients.
AIS)(NASDAQ/NMS:AISX) Tuesday reported that data associated with the company's Phase II clinical trial of its AIS CELLector CD5/CD8 device was presented by the principal investigator at the American Society of Hematology's (ASH) annual meeting.
The AIS CELLector CD5/CD8, designed to reduce graft versus host disease (GvHD) by depleting T cells from donor bone marrow prior to infusion into a recipient, yielded preliminary results that indicate a low rate of acute GvHD in a high risk patient population.
The study also showed that the AIS CELLector CD5/CD8 effectively depleted T cells and minimally depleted CD34+ cells from the bone marrow of all donors.