FGFR1

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FGFR1

A gene on chromosome 8p12 that encodes fibroblast growth factor receptor-1, which has an extracellular region composed of 3 immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Binding of a ligand unleashes a cascade of downstream signals that impact on mitogenesis and differentiation.

Molecular pathology
FGFR1 mutations are associated with inherited syndromes (e.g., Antley-Bixler syndrome, autosomal dominant Kallmann syndrome 2, Jackson-Weiss syndrome, osteoglophonic dysplasia and Pfeiffer syndrome), as well as myeloproliferative disorders and stem cell leukaemia lymphoma syndrome.
References in periodicals archive ?
gariepinus was categorized as the group-synchronous type (Cek and Yilmaz, 2007).
As a rule of thumb, you should think of CEKs as usable only on "vanilla" columns or in "vanilla" code.
After being fielded, each CEK was sent to its geographic area of responsibility, and advise and assist teams were assigned to support them during their approximately 10-month training period.
Together, advisers and partners at all levels strive to provide functional advice to ANSF engineer leaders from the CEK to the Ministry of Defense.
Legal experts of BSP, however, counter that CEK has registered the GERB MPs as an initiative committee backing the "yes" position and now must take them out since currently they are proponents of the "no" one.
Xsilon is offering the HAN9000 CEK to vendors and service providers who are looking to deploy M2M services into the home environment, where existing communications technologies have failed to create a major footprint due to their poor connectivity within domestic premises.
Since research by Cek and Sereflisan (2011) on a unionoid is comprehensive.
Since evidence was not presented with the claim, the magistrates requested evidence from CEK and local commissions.
The Socialists did indeed counter some of the new rights of CEK, in addition to refusing registration a to schedule presidential elections, when a president has not been elected during the first round, or having some decisions not subject to appeal such as the way of work of local election commissions.
Contractor name : CEK CONSTRUCTION AND WATER SUPPLY
The pilot project is to involve only several election polls in the country to be decided later by the Central Election Commission (CEK).
Recent work in the CEK group has identified a number of interesting copper precursors that have been used to deposit copper.