CDw65 | definition of CDw65 by Medical dictionary
a membrane protein present on myeloid cells and some monocytic cells that is involved in signal transduction leading to formation of the respiratory burst; present in some acute nonlymphocyte leukemias.
References in periodicals archive
European Group for Immunological Characterization of Acute Leukemias (EGIL) Algorithm for Biphenotypic Blasts (a,b) Points B T Myeloid 2 cyCD79a CD3 (sm or cy) MPO cyCD22 TCR-[alpha][beta] cyIgM TCR-[gamma][delta] 1 CD19 CD2 CD117 CD20 CD5 CD13 CD10 CD8 CD33 CD10 CDw65
The European Group for the Immunological Classification of Leukaemias has proposed that acute myeloid leukemia be defined immunologically by the expression of 2 or more of the following myeloid markers: myeloperoxidase, CD13, CD33, CDw65
, and CD117.