corneal dystrophy of Bowman layer, type 1(redirected from CDRB)
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corneal dystrophy of Bowman layer, type 1An autosomal dominant (OMIM:608470) form of corneal dystrophy characterised by dusty corneal opacities and a rough, map-like surface with a peripheral condensation ring separated from the limbus by a narrow strip of normal cornea.
Has been linked to defects of TGFBI, which encodes an RGD protein that binds to type-I, -II and -IV collagens and plays a role in cell–collagen interactions.
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