GDF.af.5

(redirected from CDMP1)
Also found in: Acronyms.

GDF.af.5

A gene on chromosome 20q11.2 that encodes a member of the bone morphogenetic protein (BMP) family, which regulates cell growth and differentiation in both embryonic and adult bone and cartilage.

Molecular pathology
GDF5 mutations are associated acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type.
References in periodicals archive ?
Sequence analyses of the coding region of CDMP1 gene led to the detection of a four base-pair insertion mutation (c.
8 In conclusion, the present study gives another evidence of involvement of CDMP1 in limb morphogenesis and broadens the phenotypes associated with CDMP1 mutation in Pakistani population.
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1.