Cornelia de Lange syndrome

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de Lang·e syn·drome

a multiple congenital anomaly syndrome characterized by mental retardation, distinctive facies with microcephaly, synophrys, low anterior hairline, depressed nasal bridge, anteverted nares, long philtrum, carp mouth, thin upper lip and low-set ears, prenatal and postnatal growth retardation, hirsutism, and frequently, limb anomalies. Genetics unclear, although some instances appear to be autosomal dominantly inherited.
Farlex Partner Medical Dictionary © Farlex 2012

Cornelia de Lange syndrome

(kôr-nē′lē-ä də lăng′, də läng′, kôr-nā′lē-ä dĕ läng′ə)
A congenital disorder characterized by intellectual disability, short stature, characteristic facies with thick eyebrows and low hairline, and limb abnormalities.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Cornelia de Lange syndrome

An often autosomal dominant, multiple congenital anomaly syndrome (OMIM:122470) characterised by mental retardation; distinctive facies with microcephaly, unibrow, low anterior hairline, depressed nasal bridge, anteverted nares, long philtrum, carp mouth, thin upper lip and low-set ears; prenatal and postnatal growth retardation; hirsutism; and frequently, limb anomalies.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

de Lange,

Cornelia, Dutch pediatrician, 1871-1950.
Cornelia de Lange syndrome - Synonym(s): de Lange syndrome
de Lange syndrome - a congenital anomaly characterized by impaired development, mental retardation, characteristic facies with synophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym(s): Amsterdam syndrome; Cornelia de Lange syndrome
Medical Eponyms © Farlex 2012
References in periodicals archive ?
FMCSA said the AAMVA raised several concerns, such as wanting to know what FMCSA intends that states do with the information they receive from the clearinghouse, and what specific information would states receive in response to a request for information about a CDL holder or applicant.
Replying to a supplementary question, Shah said that the last CDL was taken in 2003-04 and after that no loan has been taken from the federal government.
Replying to a supplementary question, CM Shah said that the last CDL was taken in 2003-4 and after that, no loan had been taken from the federal government.
Only a few Chinese cases have been reported, regardless of the many CdLS cases reported worldwide.
Weight gain and heart disease are common, says Gordon Zellers, an Ohio physician who spends half his time examining truckers and administering drug tests, which increasing numbers of CDL applicants fail.
"There are a lot of vehicles like those delivery vans that FedEx and UPS drive that don't require CDLs but are considered commercial motor vehicles, which mean the same rules apply that you can't haul that [interstate] freight until you're twenty-one."
Only few reports have commented on endocrine abnormalities in CdLS. Kline et al (7) reported a mildly delayed puberty in a group of 49 patients with CdLS, with a mean age of onset of 15 years for boys and 13 years for girls.
Cornelia de Lange Syndrome (CdLS) can be expressed in multiple organ systems requiring a variety of specialists, including pediatric otolaryngology.
Cornelia de Lange syndrome (CdLS) is a rare genetic syndrome with clinical findings related to multiple organ systems such as extremities, gastrointestinal tract, skin and central nervous system [18].
Seguiu-se com a interpretacao desses fenomenos numa aplicacao pratica em um estudo multicaso (YIN, 2013), que apresentou a real caracterizacao da administracao do capital de giro das CDLs de gas natural canalizado da regiao nordeste do Brasil.