CDK7

(redirected from CDK-activating kinase)
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CDK7

A gene on chromosome 5q12.1 that encodes a cyclin-dependent kinase, an important regulator of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1 and is a key component of the transcription factor TFIIH, which is involved in transcription initiation and DNA repair.
References in periodicals archive ?
Expression and activity of p40M015, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesis.
CDK7 and CCNH are components of CDK-activating kinase and are required for meiotic progression of pig oocytes.
Thrl61 phosphorylation is carried out by CDK-activating kinase (CAK) and occurs in G2 and late M phase, after degradation of cyclin Bl (Hannon et al.