CDH1

(redirected from CDHE)

CDH1

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells.

Molecular pathology
CDH1 loss-of-function mutations correlate with gastric, breast, colorectal, thyroid and ovarian cancer, and they are thought to contribute to cancer progression by increasing proliferation, invasion and/or metastasis. CDH1 mutation causes hereditary diffuse gastric cancer and an increased susceptibility to endometrial and ovarian cancers.
References in periodicals archive ?
Garcia, who said he wasn't surprised by the research findings, has been at the forefront of addressing the equity issues as former executive director of the Colorado Department of Higher Education (CDHE) and past president of Pikes Peak Community College, a minority serving institution (MSI), and Colorado State University - Pueblo, a Hispanic serving institution (HSI).
The Georgetown Center collaborated with CDHE about what the research team might consider studying, and the topic was based on CDE's interest in an equity focus on college attainment, Fasules said.
Col Nigel Tai, Consultant Trauma and Vascular Surgeon from The Centre For Defence Healthcare Engagement (CDHE) will represent EMQ by speaking about trauma systems around the world and how Birmingham is a leader within this field.