CDH26

CDH26

A gene on chromosome 20q13.33 that encodes a calcium-dependent cell adhesion protein (cadherin) of unknown function.
References in periodicals archive ?
Nonclassical cadherins include a large number of cadherins, including CDH13, desmosomal cadherin, 7D family protocadherins, CDH23, fat-dachsous, CDH26, CDH28, flamingo, calsyntenins, and RET, which differ in a number of structural aspects, while still conforming to the basic cadherin structure.
All CDH genes (n = 27) screened in this study include CDH1 (E-cadherin), CDH2 (N-cadherin), CDH3 (P-cadherin), CDH4 (R-cadherin), CDH5 (VE-cadherin), CDH6 (K-cadherin), CDH7 (cadherin 7), CDH8 (cadherin 8), CDH9 (T1-cadherin), CDH10 (T2-cadherin), CDH11 (OB-cadherin), CDH12 (N-cadherin 2), CDH13 (H-cadherin), CDH15 (M-cadherin), CDH16 (KSP-cadherin), CDH17 (LI-cadherin), CDH18 (cadherin 18), CDH20 (cadherin 20), PCDHGA12 (CDH21), CDH22 CDH23 CDH24 DCHS1 (CDH19, or CDH25), CDH26 DCHS2 (CDH27), CDHR3 (CDH28), and CDHR4 (CDH29).
To investigate the status of CDHs in breast cancer, we screened 27 members of CDHs in TCGA datasets and found that CDH1 was indeed low expressed or mutated in 16% of TCGA samples, and other CDHs (especially CDH17, CDH4, CDH26, CDH3/8, and CDH2/6/12) were almost highly expressed or amplified (Supplementary Figure S1 in Supplementary Material at https://doi.org/10.1155/2017/5091541).