CDH19

CDH19

A gene on chromosome 18q22.1 that encodes cadherin 19, a calcium-dependent cell adhesion protein which preferentially interacts with itself in a homophilic manner and is thought to contribute to cell sorting. This is also a less preferred gene symbol for what is now designated as DCHS1, see there.
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found Schwann cell precursor marker CDH19 and Schwann cell dedifferentiation marker Sox2 were significantly upregulated in neurofibromas from diagnostic patients.
Classical cadherins can be further subdivided into the type I classical cadherins consisting of CDH1 (E-cad), CDH2 (N-cad), CDH3 (P-cad), CDH4 (R-cad), and CDH15 (M-cad); the type II classical cadherins include CDH5 (VE-cad), CDH6 (K-cad), CDH7, CDH8, CDH9 (T1-cad), CDH10 (T2-cad), CDH11 (OB-cad), CDH12 (N-cad-2), CDH18, CDH19, CDH20, CDH22, and CDH24.