The team studied the role of CD95
in tumours using several human cancer cell lines, liver cancer mouse models, and models of ovarian cancer.
About APG101 Apogenix' lead immuno-oncology candidate APG101 is a fully human fusion protein that consists of the extracellular domain of the CD95
receptor and the Fc domain of an IgG antibody.
expression on naive T cells from HIV-infected persons undergoing highly active anti-retroviral therapy (HAART) and the influence of IL-2 low dose administration, khan Study Group.
Lack ofT-cell receptor-induced signaling is crucial for CD95
ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death.
About APG101 Apogenix' lead drug candidate APG101 is a fully human fusion protein that consists of the extracellular domain of the CD95
receptor and the Fc portion of an IgG antibody.
ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95
or by TNF-alpha.
CD3, CD4, CD9, CD11, CD19, CD20, CD22, CD26, CD27, CD28, CD29, CD33, CD37, CD40, CD44, CD45, CD47, CD52u CD55, CD56, CD66, CD70, CD74, CD80, CD95
, CD98, CD100, CD117, CD135, CD137, CD152, CD200, CD223, CD227, CD246, CD248, CD274, CD276, CD279
TEHRAN (FNA)- Cancer cells - and not normal cells - can be killed by eliminating either the FAS receptor, also known as CD95
, or its binding component, CD95
ligand, scientists demonstrated.
Quotations are invited for Supply of Antibodies, Human CD44 APC G44-26 Pack size: 100 tests, Human CD95
The Newcastle researchers found that patients with the risk version of the CD95
gene had a better chance of survival if they were given an increased dose of ATRA alongside their chemotherapy.
Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95
ligand and down-regulation ofc FLIP(short).
Indeed, the lack of CD95
marker is sufficient to identify a population of naive T cells, as defined by coincidence with previously characterized CD45RA (+) CD62L (+) T cells.