Ten genes (ATP8A1, bridging integrator 2, CD93
molecule [CD93], exophilin 5, GRB2 associated binding protein 2, n-ethylmaleimide-sensitive factor attachment protein, beta, PLA2G6, PTPRC, and vesicle associated membrane protein 1 [VAMP1]) were associated with exocytosis, and five genes (ATP8A1, CD93
, DMBT1, PTPRC, and VAMP1) were classified under the secretory granule membrane term in the GO network.
Genes P value COL4A1 3.17E-08 PCDH17 7.47E-08 PECAM1 2.07E-07 IGFBP5 2.73E-07 CAV1 2.75E-07 KCNJ8 3.49E-07 PIK3R3 3.53E-07 LCN2 3.77E-07 COL6A3 4.13E-07 COL4A2 4.78E-07 HEG1 5.51E-07 CD93
6.32E-07 ADAM9 6.36E-07 RIPK2 9.92E-07 AMN 1.11E-06 ACVR1 1.11E-06 CALU 1.17E-06 CXCL6 1.32E-06 TMEM158 1.63E-06 TIMP3 1.70E-06 Table 2.
Introduction of additional markers allowed for further characterization of these subsets indicating that CD14lowCD16+ monocytes expressed higher levels of CD43, CD115, CXCL16, CXCR1 and C3AR1 expression whereas CD14highCD16- monocytes exhibited higher levels of CD1d, CD93 and CD114.
Importantly, analysis of genes associated with proliferation, differentiation and cell cycle indicated that CD16-positive monocytes represented later stage of differentiation (assessed by substantial expression of broad spectrum of markers characteristic for dendritic cells and macrophages: SIGLEC10, CD43, RARA and CD97, CD115, C3AR1 respectively) in contrast to CD16-negative monocytes demonstrating high levels of genes coding myeloid (CD1d, CD14, CD93, MNDA) and granulocyte markers (CD114, FPR1) [6,8].
interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis," Journal of Leukocyte Biology, vol.
(a) microRNA miR-516-5p miR-517 * miR-526a miR-525 miR-520a * Number of 349 179 212 340 352 predicted target genes Unique target genes Shared with miR-525 CCR2 FAS BCAP29 TOX ACVR2B CD109 IL6ST CD24 AHSA2 CD1A IL9R CD302 ATRN DNAJC25 IRAK3 CFLAR CD2 FLT1 LILRA2 DNAJC21 CD300LB IL17RE MTDH HSP90AA1 CD46 IRAK1 PAPPA IGFBP1 CD93
LILRB5 TLR2 HSF5 PDCD6IP TNFRSF19 IGF1R SOCS2 TNFSF15 IL10RA TRAF6 MMD2 PPARA TLR7 VSIG4 All the targets were predicted by a bioinformatics tool MirTarget2 using miRDB online database.
A variety of other alterations have been described in A-ASCs exposed to the magnetic fields in MRIs, including up-regulation of CD93
mRNA, lipocalin 6 mRNA, sialic acid acetylesterase mRNA, and olfactory receptor mRNA, and down-regulation of ubiquilin 1 mRNA.
The Three Grotesques for piano (1935) has been recorded in a recital of Bacewicz's piano music by Ewa Kupiec (including the Studies and her best-known piano work, the Second Sonata, 1953), although on the recording they are called Drei Burlesken (Piano Works, Hanssler Classic CD93
.034 , CD).
Transcription analysis of 44 CD genes was also carried out, indicating 24 CD genes (CD3E, CD244, CD69, CD247, CD40L, CD38, CD5L, CD44, CD5, CD83, CD163L1, CD36, CD14, CD28, CD200R1A, CD40, CD59, CD200, CD4, CD2, CD72, CD180, CD79B, and CD93
) to be markedly increased by 2.1- to 8.4-fold, and 4 CD genes (CD163, CD8A, CD34, and CD7) to be significantly decreased by 2.1- to 8.2-fold in chicken line 6.3 with p < 0.01 and fold [greater than or equal to] 2.