The dendritic cells (DCs) then recognize CRT, HMGB1, and ATP through CD91
, Toll-like receptor 4, and P2X purinoreceptor 7, respectively, and take up the cancer cells.
Impaired recognition of apoptotic neutrophils by the C1q/calreticulin and CD91
pathway in systemic lupus erythematosus.
The impact of HSP70 expression on tumor immunogenicity may be related to variable functions of CD91
molecule (HSP70 receptor).
Hoffmann et al., "C1q and mannose binding lectin engagement of cell surface calreticulin and CD91
initiates macropinocytosis and uptake of apoptotic cells," Journal of Experimental Medicine, vol.
Studies designed to provide an insight into the molecular mechanisms that account for the suppressed AM efferocytosis showed that the expression of recognition receptors, such as CD31, CD44, CD91
, CR-3, CR-4, Fc[gamma]R1, MARCO, and DC-SIGN, was significantly changed in AMs from patients with COPD [150, 226].
(8) reported that a decrease in the expression of phagocyte surface receptors, such as CD31, CD91
, and CD44, is responsible for defective efferocytosis in COPD (11).
Nestle, "Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91
during induction of psoriasis," British Journal of Dermatology, vol.
The binding between heme and hemopexin allows heme to remain soluble in an aqueous environment, and the heme-hemopexin is removed by interaction with the widely expressed LDL receptor-related protein/ CD91
is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin," Immunity, vol.