CD87

CD87

a glycosylphosphatidylinositol-anchored membrane protein present on activated T cells, monocytes, and activated neutrophils; plays a role in cell-surface plasminogen activation; expressed on macrophages at sites of inflammation.
References in periodicals archive ?
Revillod, "A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis," Arthritis & Rheumatology, vol.
Both parental lines, CD87 and Katepwa, showed stripe rust resistance.
Revillod et al., "A genetic variation located in the promoter region of the UPAR (CD87) gene is associated with the vascular complications of systemic sclerosis," Arthritis & Rheumatology, vol.
Barazzone, "Urokinase receptor (uPAR, CD87) is a platelet receptor important for kinetics and TNF-induced endothelial adhesion in mice," Circulation, vol.
(71) Furthermore, human pharyngeal cells express urokinase plasminogen activator receptor (uPAR) or CD87 on their surface that serves as a receptor for GAPDH.
Osawa et al., "Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy," Cancer Science, vol.
Steinborn, "Urokinase plasminogen activator receptor (CD87) expression of tumor- associated macrophages in ductal carcinoma in situ, breast cancer, and resident macrophages of normal breast tissue," Journal of Leukocyte Biology, vol.
Objective: The plasminogen activator system consists of the serine protease urokinase plasminogen activator (uPA), two endogenous inhibitors of PM-1 (plasminogen activator inhibitor-1) as well as the PAI-2 and uPA receptor (uPAR or CD87).
A panel of CD87, CD45, CD56, CD 10, CD19, CD20, CD38, and CD138 was tested by flow cytometry.
Results: CD87 was negative in 8 (27.5%) cases, dim positive in 9 (31.1%) and bright positive in 12 (41.4%).
Further clinical studies including large numbers of patients are needed to determine the prognostic role of CD87 in MM.
Proteolytic regulation of the urokinase receptor/ CD87 on monocytic cells by neutrophil elastase and cathepsin G J Immunol 2004;172:540-9.