CD8 cells


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Related to CD8 cells: T cells, CD8 alpha, CD4 cells

CD8 cells

T cells with CD8 on the surface, which are immunosuppressive and suppress mitogen-induced and antigen-specific antibody production, and require CD4 cell cooperation
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References in periodicals archive ?
A small case-control study determined that aging HIV-infected people (median 56 years) with a good CD4 count (median 724 cells/mm (3)) and long-term viral suppression with antiretroviral therapy have CD4 and CD8 cells similar to those of a substantially older HIV-negative comparison group (median 88 years) and utterly unlike those of a younger HIV-negative group (median 27 years).
What speeds aging with HIV--and what can be done about it?
Both groups had similar concentrations of CD8 cells. These cells destroy damaged or infected cells by releasing a torrent of chemicals that take apart target cells.
Immune protein may stall HIV. (Immunology)
According to our results patients with more severe form of disease had the lowest number of both CD4 and CD8 cells which can be a sign of suppressed cellular immunity in these patients.
CD4+ cell counts in patients with different clinical manifestations of tuberculosis
The team also found that SIV creates such mutants in response to the assault by CD8 cells at about the same rate as HIV does.
Original HIV infection holds its sway despite numerous changes
These are CD4 cell factors that are necessary to turn on the CD8 cells (cytotoxic T lymphocytes).
A look at HIV immune research
Three research groups now challenge that dogma with evidence showing that under certain conditions, CD8 cells can make the CD4 protein and consequently become infected by the AIDS virus.
AIDS virus may feast on an unexpected meal
The engineered stem cells developed into a large population of mature, multifunctional HIV-specific CD8 cells that could specifically target cells containing HIV proteins.
Stem cells can be engineered to kill HIV
Levy and others quickly established that CD8 cells can secrete one or more soluble molecules that hinder HIV.
Body's proteins suppress AIDS virus
They treated the CD8 T-cells with TAT2 and combined them with the CD4 T-cells in the dish-and found that the treated CD8 cells inhibited production of HIV by the CD4 cells.
Medicinal plant may harbour HIV cure
To identify what was inhibiting HIV production in asymptomatic patients, the team separated the T cells into CD4 cells, which help trigger immune responses and which form the target of HIV infection, and CD8 cells, which destroy infected cells.
Immune factor inhibits the spread of HIV
The Stanford team found similar numbers of CD8 cells in the two groups.
HIV attack destroys immune innocence
Normally, these CD8 cells kill other cells and make interferon gamma, a TH1 messenger.
Number 12 steps up to bat; will this immune system messenger hit a grand slam?

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