CD8 cell


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CD8 cell

a T lymphocyte that secretes large amounts of gamma-interferon, a lymphokine involved in the body's defense against viruses. CD8 cells prevent the unnecessary formation of antibodies. Also called cytotoxic T cell. See also CD4.

CD8 cell, CD8+ cell

a major classification of T lymphocytes, referring to those that carry the CD8 antigen; the major subtypes are the cytotoxic T lymphocytes and the suppressor cells. Also called CD8 T lymphocytes.

CD8 cell

A suppressor T cell, e.g., a cytotoxic T cell.
See also: cell
References in periodicals archive ?
TAT2 (GRN 163L), a small-molecule telomerase activator, "modestly" retarded telomere shortening while enhancing antiviral activity of CD8 cells collected from people with HIV.
Gallo of the University of Maryland's Institute of Human Virology in Baltimore and his colleagues report that when CD8 cells are stimulated out of their quiescent state, as they would be when responding to an infection, they make CD4.
But in a small group of HIV-infected people known as long-term nonprogressors, those CD8 cells seem to stave off the development of AIDS, even in the absence of anti-HIV drugs.
But in the US study, the CD8 cells suppressed the virus without killing the healthy CD4T cells.
Overall, they found that the telomere length of CD8 cells was significantly shorter than CD4 telomere length in a group of 14 HIV-infected men, suggesting the new CD8 cells were being produced much faster than CD4 cells.
CD4 immune cells attack disease-causing intruders, while CD8 cells suppress the attack.
Many potential vaccines stimulate an antibody response but not the CD4 and CD8 cells necessary for full protection from disease, says Beltz.
Specifically, rhIL-7 blocks sepsis-induced depletion of CD4 and CD8 cells, enhances lymphocyte recruitment, prevents the sepsis-induced loss in immunity as evidenced by preserved delayed-type hypersensitivity response, does not exacerbate the proinflammatory response in sepsis, and clearly improves survival.
high]/CTLA-4-positive CD8 cells as compared with men (mean, 16.
We will examine the effect of triggering innate responses in DC using HIV-1 mutants/drug treated wild type virus on allogeneic responses, by measurement of T cell proliferation and function and in an ex vivo CD8 T cell killing assays using peripheral blood CD8 cells from HIV-1 infected patients.
After the infusion, the CD8 cells in the infected mice revived and the levels of virus in their bodies decreased by a factor of four after a month.
By looking at the numbers of CD4 and CD8 cells, checking the ratio between them and measuring the cytokine production, one can tell if a patient has HIV in only a few seconds.