cytotoxic T cell

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Related to CD8 T cells: CD4 T cells, Cytotoxic T lymphocytes

cytotoxic T cell

The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cytotoxic T cell

A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell
See also: cell
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
IL-10 is required for optimal CD8 T cell memory following Listeria monocytogenes infection.
The publication ofwork in the mid 1990s suggesting that CD38 expression on CD8 T cell subsets had prognostic significance expanded the field of study and introduced other methods to define and measure CD38 expression on CD8 T cells.
On this measure, Glycyrrhiza increased the total number of all the immune cells ie CD4 T cells, CD8 T cells, B cells, and NK cells.
Indeed, a consensus is that if the immune system is still fairly intact, therapy interruption might indeed boost CD8 T cell responses, which likely contain HIV longer.
As expected, CD8 T cells produced large amounts of these enzymes upon stimulation with PMA/ionomycin.
The study focused on a particular type of 'killer' white blood cell, called CD8 T cells, which are critical tumour-fighting cells.
Murali-Krishna et al., "Rapid demethylation of the IFN-[gamma] gene occurs in memory but not naive CD8 T cells," The Journal of Immunology, vol.
The study involved killer cells, known as CD8 T cells, and their instructor cells, known as antigen-presenting cells.