CD8 cell

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Related to CD8+ cell: Cytotoxic T lymphocytes

CD8 cell

A suppressor T cell, e.g., a cytotoxic T cell.
See also: cell
References in periodicals archive ?
Further, regarding CD8+ cells, the IBS-D group had a lower number of cells in the rectum compared with the controls (45.2[+ or -]25 vs.
To further establish the role of STAT4-deficiency in T cell subsets, we adoptively transferred STAT4-deficient CD4+ or CD8+ cells in Rag1-/- mice.
To further determine whether IgE levels vary according to the progression of MPP, and to determine whether additional immunological markers also may be modulated over the course of this infection, we measured the serum levels of IgE, IL-4, IL-6, IL-10, and INF-[gamma] and the percentages of CD3+, CD4+, and CD8+ cells in the acute and recovery phases of MP pneumonia as compared to non-MPP patients and normal controls (Table 1).
Additionally, newly-reported analyses showed increased CD8+ T cell density at the tumor interface, with the total density of CD8+ cells inside the tumor boundary area increased four-fold compared with baseline; increased numbers of cells expressing CD3 antigens, a pan T-cell marker, within tumor borders, and decreased expression of VISTA, a checkpoint molecule that inhibits T-cell activation and proliferation; increases in multiple chemoattractant factors in serum, consistent with increased trafficking of immune cells post CXCR4 inhibition.
We found a significantly lower proportion of CD8+ cells and a significantly higher Foxp3+/CD8+ ratio in LNs affected by adenocarcinoma versus LNs free of metastases.
CD8+ cells were mainly distributed inside and under the epithelium (Fig.2-2) and CD4+ cells were scattered in the autologous matrix (Fig.2-3).
Data from the literature report that the expression of CD4+ and CD8+ cells is similar in the paucibacillary (tuberculoid) and multibacillary (histoid) forms (10).
Thus increased receptor expression of CD95+ was found in CD4+, CD8+ cells and natural killers, both CD16+ and CD56+ cells.
After the treatment the number of CD8+ cells decreased more than 2 times.
Within the T lymphocyte subpopulation, CD4+ cells, which trigger the immune response cascade and CD8+ cells, which undertake the effector functions of cell-mediated immunity, are the two main cell types.
It inhibits cytokine production in Th1 and CD8+ cells, but not in Th2 cells.
A protein produced by CD8+ cells of the adaptive immune system is exerting potent viral-suppressive activity through a mechanism thought to be reserved for cells of the innate immune system," said a co-author of the study.