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a type I transmembrane protein found on suppressor (cytotoxic) T cells, some natural killer cells, and most thymocytes that is involved in T-cell antigen recognition; expressed in some T-cell lymphomas and large granular lymphocyte leukemias.
Farlex Partner Medical Dictionary © Farlex 2012
A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
CD8T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells, and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.