CD8


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CD8

a type I transmembrane protein found on suppressor (cytotoxic) T cells, some natural killer cells, and most thymocytes that is involved in T-cell antigen recognition; expressed in some T-cell lymphomas and large granular lymphocyte leukemias.

CD8

(sē′dē-āt′)
n.
A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.

CD8

T8 antigen A disulfide-linked heterodimeric protein, for which each monomer is 32–34 kD; CD8 is a marker for T cells with suppressor and cytotoxic activity; it is a co-receptor with class I MHC antigens on antigen-presenting cells, and is physically associated with a p56 tyrosine kinase, which phosphorylates adjacent proteins; NK cells may weakly express CD8. See Cytotoxic T cells.

CD2

cluster of differentiation or cell differentiation glycoproteins.

CD antigen
a group of cell surface molecules which act as markers on T lymphocytes.
CD3
found on T helper (Th) and T cytotoxic (Tc) lymphocytes; associated with signal transduction.
CD4
found on T helper lymphocytes; an adhesion molecule that binds to class II MHC molecules.
CD8
found on T cytotoxic and variably on NK lymphocytes; an adhesion molecule that binds to class I MHC molecules.
References in periodicals archive ?
Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.
Activation of memory CD8 T cells upregulates CD38 expression, which makes it a good marker of cellular activation in this subset.
Mycobacterium tuberculosis specific CD8 T cell preferentially recognize heavily infected cells.
On this measure, Glycyrrhiza increased the total number of all the immune cells ie CD4 T cells, CD8 T cells, B cells, and NK cells.
Durante la fase aguda de la infeccion viral se desarrolla una respuesta vigorosa de linfocitos T CD8 oligoclonal (3, 4), la cual alcanza su valor maximo cuando la viremia primaria comienza a descender (5, 6).
Investigations with CD4 and CD8 antibodies were performed each with one donor in nearly the same manner.
Aurelian notes that both dl5-29 and Delta PK hike production of a CD8 T cell protein called interferon gamma.
Indeed, a consensus is that if the immune system is still fairly intact, therapy interruption might indeed boost CD8 T cell responses, which likely contain HIV longer.