CD77

CD77

a membrane protein present on germinal center B cells, follicular dendritic cells, endothelium, and some epithelial cells which may act as a receptor for toxins of Escherichia coli or Shigella dysenteriae; expressed in Burkitt lymphomas and B-cell lymphomas of follicular center cell origin.
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Extensive research has identified the glycosphingolipid globotriaosyl ceramide (Gb3 or CD77) as the receptor for Shiga toxin (verotoxin) and the bacterial pilin papG protein.
At $8,500.00 for the CD player or the integrated amplifier, many will argue the value, but if you inspect the build quality and the features of the Abingdon Music Research CD77 player you can better understand the pricing structure.
For example, Stx binds to the cell surface glycolipid CD77, which is expressed by B cells in certain B-cell lymphomas (65,66).
Determining the specific gene and subsequent protein expression related to apoptosis pathways in these cell lines will provide insight into pathways that involve CD77. For microarray analysis, total RNA was isolated, labeled with Cy3, and hybridized to Agilent Human Whole Genome microarrays.