CD73

CD73

a glycosylphosphatidylinositol-anchored membrane protein present on some B cells, some T cells, thymocytes, some epithelial and endothelial cells, and dendritic cells; expressed on most B-cell acute lymphoblastic leukemias, breast carcinomas, and large granular leukocyte leukemias.
References in periodicals archive ?
Respecto de la expresion del mRNA con el marcador CD73, como control de amplificacion se evidenciaron los amplicones de las amplificaciones de CD73 y GAPDH en un gel de agarosa tenido con bromuro de etidio (Figura 3B).
The MSC surfaces were positive for CD73, CD90, and CD105 (MSC markers) but negative for CD34 and CD45 (hematopoietic markers) (Figure 1).
The drug works by harnessing a molecule called CD73 that the body naturally uses to fight inflammation.
Celulas do liquido amniotico obtidas durante o pre-natal de mulheres mantiveram suas caracteristicas iniciais como a aderencia ao plastico, morfologia fibroblastoide, a expressao dos marcadores CD73, CD105, CD44, CD29, CD90 e CD13, a nao expressao dos marcadores CD45 e CD34 bem como viabilidade de 80% mesmo apos a criopreservacao pelo periodo de 5 meses, quando foram descongeladas e recultivadas com sucesso apos ao nascimento do bebe, visando sua aplicacao na medicina regenerativa neonatal (22).
Currently, only 9 individuals are known to have the disorder, dubbed 'artificial calcification due to CD73 deficiency'.
Cells were incubated for 1 h at 4[degrees]C with the PE-conjugated mouse monoclonal antibodies against rat CD45, CD73 and CD90, FITC-conjugated mouse monoclonal antibodies against rat CD34 and CD44, and PerCP-conjugated mouse monoclonal antibodies against rat CD14.
Las CSM, a diferencia de las celula "stem" hematopoyeticas (CSH), no expresan un antigeno unico y especifico para su identificacion, generando controversia en su caracterizacion; por esta razon, la Sociedad Internacional de Terapia Celular (ISCT, Internacional Society Cellular Therapy) ha propuesto tres criterios para la caracterizacion "in vitro" de CSM, estos son: 1) Demostrar el aislamiento de celulas con morfologia fibroblastoide de tipo adherente "in vitro" 2) Determinar la expresion de los antigenos CD105, CD73 y CD90, en ausencia de marcadores hematopoyeticos como CD45, CD34, CD14 o CD11b, CD79 o CD19 y HLA-DR e 3) Inducir la diferenciacion "in vitro" de las CSM en osteoblastos, adipoblastos y condroblastos (9-11).
Using the DACs and high precision clock from Arcam's award winning CD73, digital sources are processed with extremely high precision allowing fine detail to be reproduced with breathtaking clarity.
Since is seems like it is complicated (and expensive) to make a multi-format player without compromising the quality of basic CDs, many companies are introducing new CD-only players, and Arcam's DiVA CD73 and CD192 are two of the most impressive of the "affordable" bunch.
Faces are dry drilled by Joy CD73 electro-hydraulic, twin boom jumbos, using auger steels and wing bits.
Arcus's other programs include AB154, an anti-TIGIT antibody, which is being evaluated in a Phase 1 trial as monotherapy and in combination with AB122, and AB680, a small-molecule inhibitor of CD73, which is in a Phase 1 healthy volunteer study.
Cells in the fourth passage were incubated in primary antibodies as follows: in mouse and rat monoclonal CD45(1:100, BD Biosciences, USA), mouse monoclonal CD34 (1:100 BD Biosciences, USA), mouse monoclonal CD73 (1:100, BD Biosciences, USA) and mouse monoclonal CD90 (1:100 BD Biosciences, USA) antibodies for 40 min at 4[degrees]C.