CD7

CD7

a type I transmembrane protein found on thymocytes, some T cells, monocytes, natural killer cells, and hemopoietic stem cells; expressed in patients with mycosis fungoides, some patients with T-cell acute lymphoblastic lymphoma, and a few patients with acute nonlymphocytic lymphoma.

CD7

An immunoglobulin embedded within a cell membrane, expressed on the surface of mature T lymphocytes and thymocytes.
See: cluster of differentiation
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The monoclonal antibodies (MoAb) used for diagnosis of AL were: for B-lineage: CD19, CD22, CD20, CD10, for T-lineage: CD2, CD3, CD5, CD7, CD4, CD8, for myelo-monocytic lineage: CD13, CD33, CD11c, CD64, CD14, other cells surface markers: CD34, CD117, HLA-DR and intracellular MoAb: CD79a, CD3 and MPO.
However, it is common for acute leukemias to aberrantly express protein markers more typically associated with other lineages, for example, expression of the myeloid markers CD13 and CD33 in B-ALL or T-ALL and expression of the T/NK-cell markers CD7 and CD56 in AML.
A peripheral blood sample is submitted for flow cytometric immunophenotyping using 5 reagent tubes: CD2-FITC/CD56-PE/ CD7 ECD/CD5-PC5.
There are reports about T-cell receptor clonality in PL lesions and its similarity and association with lymphomatoid papulosis and mycosis fungoides, and the presence of CD30-positive and CD7 deletions," she said.
Office, Single Room Occupancy Dwellings in CD7 Presentation,
The lymphoid cells were negative for CD7, CD8, TCR-[gamma][delta], and for NK cell and B-cell markers.
Scania AB has opened the new CD7 climatic wind tunnel test facility, located at the Scania Technical Center in Sodertalje, Sweden.
Immunochemistry stain of biopsies from stomach mucosa and cervical lymph node showed CD20 (+), CD10 (+), PAX-5 (+), CD3 (−), CD7 (−), TDT (−), CD99 (−), mum-1 (−), BCL-2 (−), BCL-6 (minor+), and Ki-67 99% (+).
Flow cytometric immunophenotyping of peripheral blood samples showed positive CD3 and CD7 expression.
Individuo 1 Individuo 2 Individuo 3 Individuo 4 VC1 4 4 0 3 VC2 4 4 0 3 VC3 4 4 0 3 VC4 4 4 0 3 VC5 4 4 1 3 VC6 4 2 0 3 VC7 4 4 0 3 VT1 4 4 4 0 VT2 4 3 4 3 VT3 4 3 3 3 VT4 4 3 3 3 VT5 4 4 4 0 VT6 4 3 3 0 VT7 4 3 0 3 VT8 4 3 4 0 VT9 4 3 4 0 VT10 4 2 0 3 VT11 4 3 3 0 VT12 4 4 4 0 VL1 4 4 0 3 VL2 4 3 0 3 VL3 4 3 0 3 VL4 4 4 0 3 VL5 4 3 0 3 CD1 4 4 4 0 CD2 4 3 0 0 CD3 4 3 3 0 CD4 3 3 3 0 CD5 4 3 2 0 CD6 4 3 3 0 CD7 4 3 2 2 CD8 4 3 2 0 CD9 4 3 2 0 CD10 4 3 2 0 CD11 4 4 0 0 CD12 4 4 0 0 CI1 0 4 4 0 CI2 4 3 3 0 CI3 4 3 0 0 CI4 4 3 2 4 CI5 4 3 2 0 CI6 4 3 3 0 CI7 4 3 3 0 CI8 4 4 2 0 CI9 4 4 3 0 CI10 4 3 0 0 CI11 4 4 3 0 CI12 4 3 0 4 Tabla 4.
After applying a protein block (10 minutes), a standard immunohistochemistry (IHC) technique was performed with prediluted mouse monoclonal antibodies TIA-1 (clone TIA-1), PAX5 (clone BC-24), CD7 (clone LP15), CD4 (clone BC/1F6) + CD8 (SP16) rabbit monoclonal antibody (prediluted double stain cocktail), or rabbit polyclonal antibody CD3.