The expression of CD69 molecule
is not restricted to activated lymphocytes, as activated neutrophils and eosinophils can also express CD69.
There are, however, few studies in the literature that assess the function of the CD69 molecule
expressed on T lymphocytes in individuals infected with S.
We also evaluated T cell- and NK cell-related genes, including CD3D [CD3d molecule, delta (CD3-TCR complex)], CD69 (CD69 molecule
), PRF1 [perforin 1 (pore forming protein)], GNLY (granulysin), CCR3 [chemokine (C-C motif) receptor 3], KLRK1 (killer cell lectin-like receptor subfamily K, member 1), IDO1 (indoleamine 2,3-dioxygenase 1), and KLRD1 (CD94) (killer cell lectin-like receptor subfamily D, member 1).
in human neutrophils: its expression and role in signal-transducing mechanisms.
The CD69 molecule, the earliest marker of T cell activation, is a member of the C-type animal lectin superfamily of signal transmitting receptors and has recently been cloned [9, 10].
As shown in the Table, the proliferation through the CD69 molecule in the presence of submitogenic doses of PMA (2ng/ml) was also decreased in the elderly (16914 vs.
We assessed the expression and functionality of the CD69 molecule, the earliest surface antigen appearing after T cell activation .
Ouabain, at the concentration of [10.sup.-7] M, promoted an increase on the percentage of [CD69.sup.+] monocytes (Figure 1(a)) and a very small increment on the mean density of CD69 molecules
per cell (data not shown).