CD69 antigen | definition of CD69 antigen by Medical dictionary
CD69 (redirected from CD69 antigen)
a type II transmembrane protein present on platelets, CD4-positive or CD8-positive thymocytes, activated lymphocytes, and activated T or natural killer cells that functions as a signal transducer, enhancing cell activation and/or platelet aggregation.
CD69 A gene on chromosome 12p13 that encodes a member of the calcium-dependent lectin superfamily of type-II transmembrane receptors, the expression of which is induced by T-cell activation. CD69 is involved in lymphocyte proliferation and acts as a signal-transmitting receptor in lymphocytes, natural killer (NK) cells and platelets.
References in periodicals archive
* CD69 antigen expression test (Nakamura et al., 1989).
Instead of the classical T-lymphocyte proliferation test, we used the CD69 antigen expression test (Nakamura et al.
The expression and function of the CD69 antigen
was compared between healthy elderly and young subjects.