CD68


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CD68

a type I transmembrane protein present on monocytes, macrophages, osteoclasts, mast cells, cytoplasmic granules, activated platelets, and large lymphocytes; expressed in neuroma Schwann cells, in nerves undergoing wallerian degeneration, in myeloid cell tumors, and in anaplastic lymphomas and epithelial tumors.

CD68

A glycoprotein expressed on monocytes and tissue macrophages.
See: cluster of differentiation
References in periodicals archive ?
The second patent covers a diagnostic test based on measurement of the abundance of a single protein, known as CD68, in tumor samples.
On immunohistochemistry, RDD was positive for both S-100 and CD68 proteins but negative for CD1a.
CD163 and CD68 immunostains demonstrated intensely positive staining in the hyperplastic population of stromal cells of both secondary and tertiary villi, confirming their identity as stromal macrophages, or Hofbauer cells.
The histiocytes stain positively for the CD68 antibody.
However, a dIF assay using NN-Ab01 and an antibody against CD68 (#M0814; Dako), a macrophage marker, showed WU-VP1 and CD68 single-positive cells but no double-positive cells.
The giant cells and pleomorphic polygonal cells were dyed as vimentin positive in immunohistochemical dye CD68 (Fig.
CD31 (Figure 1-F), CD68, and factor VIII-related antigen (Figure 1-E) highlighted the lesion.
These histiocytes were positive for S-100 protein (figure 1), CD68, HAM-56, and lysozyme, and they showed emperipolesis.
The bone marrow core biopsy showed normal cellular components and abundant hemophagocytic macrophage infiltration based on CD68 immunohistochemical staining.
2C), CD99, smooth muscle antibody, and bcl-2, but not cytokeratin (Fig-2D), co-factor, epithelial membrane antigen, desmin, myogenic differentiation antigen 1, S-100, actin, or CD68.
We used the following cDNAs: human LOX-1 (GenBank NM002543), SR-A (GenBank NM002445), CD36 (GenBankNM000072), SR-BI (GenBank NM005505), CD68 (GenBank NM001251), and dectin-1 (GenBank NM197947), which were subcloned into pcDNA6.