CD66a

CD66a

a type I transmembrane protein, present on neutrophils, histiocytes, some myeloid progenitor cells, and the brush border of colonic epithelial cells; facilitates adhesion and neutrophilic activation; expressed in chronic myelocytic leukemia and some cases of acute lymphocytic leukemia.
References in periodicals archive ?
Shively, "Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F," Journal of Cell Science, vol.
Neumaier et al., "CD66a (BGP), an adhesion molecule of the carcinoembryonic antigen family, is expressed in epithelium, endothelium, and myeloid cells in a wide range of normal human tissues," Journal of Histochemistry & Cytochemistry, vol.
Watt et al., "Regulation of human intestinal intraepithelial lymphocyte cytolytic function by biliary glycoprotein (CD66a)," The Journal of Immunology, vol.
Shively, "Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells," Anticancer Research, vol.
Chai, "The expression of CD66a and possible roles in colorectal adenoma and adenocarcinoma," International Journal of Colorectal Disease, vol.
Earley et al., "Tumor-suppressive activity of CD66a in prostate cancer," Cancer Gene Therapy, vol.
In a different study, the possible receptors for Gal-3 were identified as CD66a and CD66b, which are localized in gelatinase and specific granules in resting neutrophils, and are exposed on the cell membrane after priming [57].
Karlsson, "Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils," Journal of Immunology, vol.
CEACAM1 (also referred to as C-CAM, biliary glycoprotein BGP, and CD66a) is a complex glycoprotein linked to the cell membrane by a carboxy-terminal transmembrane anchor; it belongs to the carcinoembryonic antigen (CEA) family of the immunoglobulin superfamily.
Scheffrahn et al., "CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes," European Journal of Immunology, vol.
(10.) Szekanecz Z, Haines GK, Harlow LA, et al: Increased synovial expression of the adhesion molecules CD66a, CD66b and CD31 in rheumatoid and osteoarthritis.