CD64


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CD64

a type I transmembrane protein present on monocytes, megakaryocytes, and activated neutrophils that acts as a high-affinity receptor for IgG; present in some cases of acute nonlymphocytic leukemia.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Neutrophil CD64 expression, procalcitonin and presepsin are useful to differentiate infections from flares in SLE patients with SIRS.
Are neutrophil CD64 expression and interleukin-6 early useful markers for diagnosis of acute appendicitis?
Lineage-specific markers, including myeloid (CD13, CD33, CD117, MPO), monocytic (CD11b, CD14, CD64), megakaryocytic (CD61), B-cell (CD19, CD10, CD20) and T-cell (CD3) antigens, were negative.
Eight-color MFC was performed in all patients as a routine clinical test on BM samples that were obtained as part of baseline assessment at the time of diagnosis, the end of the first and second courses of chemotherapy, as well as pre-HSCT.[8],[18] A panel of eight antibody combinations that recognize CD7, CD11b, CD13, CD14, CD16, CD19, CD33, CD34, CD38, CD41, CD45, CD56, CD61, CD64, CD71, CD117, CD123, and HLA-DR was used for MRD detection, and 0.2-1 million events per tube were acquired on a Fluorescence activated cell sorter (FACS Canto II) (BD Co., USA).
(17) In regard to cell surface receptors, one leading candidate is neutrophil CD64 expression, which has so far shown good performance as a potential diagnostic marker in the evaluation of infection and sepsis.
In Acute Myeloid Leukemia with maturation CD64 was expressed which was uncommon.
Folate, CD64, NCA90, and CD15 receptors expressed on macrophages, leukocytes, and granulocytes can serve as targets.
Inflammatory markers, such as CRP, CD64, IL-6, and leukocytes, also have some diagnostic value.
Other utilized markers include HAM56, CD14, CD64, CD15, lysozyme, alpha-1 antitrypsin, and IL-2 [1-6].
MS masses express lysozyme, Ki67, and myeloid/monocytoid antigens (CD13, CD14, CD33, CD64, CD68, and c-Kit (CD117)) [4].