CD62l


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Related to CD62l: CD69, CD44, CCR7

CD62l

a type I transmembrane protein present on B cells, T cells, neutrophils, thymocytes, monocytes, eosinophils, erythroid and myeloid progenitor cells, and natural killer cells; functions as a peripheral lymph node homing receptor and facilitates binding to endothelium at inflammatory sites; found on many malignant leukocytes.

SELL

A gene on chromosome 1q23-q25 that encodes l-selectin, a cell surface adhesion/homing receptor required for binding and rolling of leukocytes on endothelial cells, facilitating leukocyte migration into secondary lymphoid organs and inflammation sites. 

Molecular pathology
SELL polymorphisms are associated with various diseases, including IgA nephropathy.
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In the present study, we investigated the co-expression of CD25 and CD62L (adhesion molecule, L-selectin) of bovine [CD4.
1] IL-2 receptor (activated T cells) CD62L Du1-29 Ig[G.
For example, monocyte expression of CD1 lb, CD54, and CD62L was higher in subjects with asthma than in healthy subjects.
Expression of CD62L on PMNs increased in males but not females (exposure-sex interaction, p = 0.
LN cells were stained with monoclonal antibodies against CD3, CD44, and CD62L (BD PharMingen, San Diego, CA).
We next asked if cutaneous beryllium, the salt solution and the oxide particles, could induce LN T-lymphocyte activation, as measured by changes in CD44 and CD62L expression.