CD61


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CD61

a membrane protein present on platelets, megakaryocytes, endothelial cells, osteoclasts, and uterine cells; facilitates platelet aggregation and adhesion.

CD61

This term is generally preferred by immunologists and pathologists; the preferred HUGO symbol for the gene is ITGB3, see there.
References in periodicals archive ?
CD61, also known as GPIIIa, is a 110 kDa glycoprotein that belongs to integrin family of proteins.
One study limitation is the lack of a gold standard (like CD61 based platelet estimate) to assess the accuracy of the obtained results.
Alternatively, using CD61 monoclonal antibodies conjugated with a fluorescent label provides absolute specificity to ensure reliable results at very low counts.
The monoclonal antibodies used were T-cell lymphoid markers (CD2, CD3, CDS, and CD7), B-cell lymphoid markers (CD10, CD19, and CD20), myeloid markers (CD13, CD33, CD14, CD61, CD117, and myeloperoxidase), and common progenitor markers (CD34 and HLA-DR).
Yine tani amaci ile agregometrenin yaninda akim sitometri incelemesinde CD41 ve CD61 monoklonal antikorlari kullanilarak glikoprotein (GP) IIb-IIIa duzeylerinin normalden dusuk oldugu belirlenebilir (Sekil 1).
A periodic acid-Schiff (PAS) stain (a) is used for comparison against a panel of immunohistochemical stains, including leukocyte common antigen (b), myeloperoxidase (c) and CD61 (d), lymphoid, myeloid and megakaryocytic elements, respectively.
CD61, which stains positively in disease states of AMKL and also stains positive for blasts in transient myeloproliferative disorder, demonstrated a weak 1+.
CD51 and CD61 were mild to moderately expressed on SLL, vascular endothelium and smooth muscle.
The first product of this alliance is an immunological platelet analysis assay, utilizing Becton Dickinson's CD61 monoclonal antibody and proprietary reagent technology, and Abbott's CELL-DYN(R) 4000 hematology system.
Specific antigens can be demonstrated by flow cytometry that may be used to further subclassify AML, such as CD64 in acute monocytic/monoblastic leukemia and CD61 in acute megakaryoblastic leukemia.