, also known as GPIIIa, is a 110 kDa glycoprotein that belongs to integrin family of proteins.
One study limitation is the lack of a gold standard (like CD61
based platelet estimate) to assess the accuracy of the obtained results.
Alternatively, using CD61
monoclonal antibodies conjugated with a fluorescent label provides absolute specificity to ensure reliable results at very low counts.
expression was higher in the rats exposed to GEE than in the control animals (Fig.
The monoclonal antibodies used were T-cell lymphoid markers (CD2, CD3, CDS, and CD7), B-cell lymphoid markers (CD10, CD19, and CD20), myeloid markers (CD13, CD33, CD14, CD61
, CD117, and myeloperoxidase), and common progenitor markers (CD34 and HLA-DR).
Yine tani amaci ile agregometrenin yaninda akim sitometri incelemesinde CD41 ve CD61
monoklonal antikorlari kullanilarak glikoprotein (GP) IIb-IIIa duzeylerinin normalden dusuk oldugu belirlenebilir (Sekil 1).
As celulas expressaram o marcador de pluricelularidade Oct-4 e os marcadores CD29, CD73, CD90 e CD 105, nao expressando os marcadores CD31, CD45 e CD61
A periodic acid-Schiff (PAS) stain (a) is used for comparison against a panel of immunohistochemical stains, including leukocyte common antigen (b), myeloperoxidase (c) and CD61
(d), lymphoid, myeloid and megakaryocytic elements, respectively.
, which stains positively in disease states of AMKL and also stains positive for blasts in transient myeloproliferative disorder, demonstrated a weak 1+.
CD51 and CD61
were mild to moderately expressed on SLL, vascular endothelium and smooth muscle.
The first product of this alliance is an immunological platelet analysis assay, utilizing Becton Dickinson's CD61
monoclonal antibody and proprietary reagent technology, and Abbott's CELL-DYN(R) 4000 hematology system.
Specific antigens can be demonstrated by flow cytometry that may be used to further subclassify AML, such as CD64 in acute monocytic/monoblastic leukemia and CD61
in acute megakaryoblastic leukemia.