CD58


Also found in: Wikipedia.

CD58

a membrane protein present on many hemopoietic cells and fibroblasts that acts as a ligand for CD2 and may be involved in T-cell function.
Mentioned in ?
References in periodicals archive ?
HLA-DR, CD58, CD99, CD56, CD38, cy-MPO, CD11b, CD13, CD33, CD65, CD64, CD117, CD36, CD61, CD4, and 7.1 were positive, and CD14, CD15, CD19, CD10, CD20, CD3, and CD7 were negative.
Several studies determined that rs1016140 in CD58 gene was associated with reduced T cell activity [39, 40].
As to the potential pig ligands of CD2, that is, orthologs of CD58 (LFA-3) and CD59, blocking with anti-pig CD58 efficiently inhibited lysis of porcine targets by human PBMC to the same extent as anti-CD2 [98, 99].
Zamani, "Association of CD58 polymorphism with multiple sclerosis and response to interferon ft therapy in a subset of Iranian population," Cell Journal, vol.
Repeat bone marrow biopsy and aspirate (Figure 1(a)) showed 64% myeloblasts which expressed a slightly different immunophenotype than originally (CD13, CD33, CD15, CD58, CD117, and HLA-DR).
It has been also reported that CD58 and CD117 were expressed by both bone marrow and adipose tissue mesenchymal stem cell populations [94].
Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.
Las moleculas de reconocimiento inmunologico como la beta2microglobulina (componente de las moleculas de histocompatibilidad clase I presentes en las celulas nucleadas) y CD58 (molecula de adhesion expresada en las celulas presentadoras de antigeno especialmente en los macrofagos) se han identificado tanto en LBDCG de fenotipo GCB como de fenotipo ABC, lo que involucra el control inmunologico como otro mecanismo linfomagenico (9).
CD58 (lymphocyte function-associated antigen-3) molecule and/or FK506 binding protein were highly expressed on the cell membrane by LO1 (249-264) and UK (311-326) [61, 62].
TRICOM consists of costimulatory molecules, including ICAM (intercellular addition molecules)-1 (CD54), B7.1 (CD80), and leukocyte function-associated antigen-3 (LFA-3)(CD58) [51].
La subpoblacion de Treg CD8+ CD28-tambien actua sobre las CDs, disminuyendo la expresion de moleculas co-estimuladoras dependientes de NF-Kb, tales como CD40, CD80, CD86 y CD58 e incrementando la expresion de receptores inhibitorios como "immunoglobulin like transcript" 3 (ILT3) e ILT4, promoviendo que aquellas Th CD4 + que interactuen con estas CDs se conviertan en celulas anergicas (16).
* CD10 Fluorescein Isothiocyanate(FITC), CD34 (FITC), HLA DR (FITC), CD29 (FITC), CD38 R-Phycoerythrin, CD22 (PE), CD20 (PE), CD58 (PE), CD 19 Allophycocyanin (APC), CD45 R-Phycoerythrincyanin 5.1(PC 5).