CD54

CD54

a type I transmembrane protein present on leukocytes and endothelial cells and inducible on lymphocytes, dendritic cells, keratinocytes, chondrocytes, fibroblasts, and epithelial cells; acts as a ligand for CD11 and CD18 and aids in intercellular adhesion.
Farlex Partner Medical Dictionary © Farlex 2012

ICAM1

A gene on chromosome 19p13.3-p13.2 that encodes a cell surface glycoprotein expressed on endothelial cells and cells of the immune system. It binds to integrins CD11a/CD18 or CD11b/CD18, and serves as a cell receptor for rhinoviruses.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Intercellular adhesion molecule-1 (ICAM-1, CD54) is increased in adhesive capsulitis.
Evaluation of the phenotypic characterization of MSC, derived from bone marrow tissue, indicated the expression of CD90 (clone 0x-75 mouse), CD73 (clone 5 F/ B9 mouse), and CD54 (clone 1A29 mouse) in 86.8%, 94.0%, and 95.1% of the cells, respectively, while CD45 was not expressed in 97.0% of the cells confirming its classification.
DC in MDS express lower levels of CD1a, CD54, CD80, and MHC II molecules [26].
Comparing y-irradiation of Drosophila APCs or UVDEX treatment by the FACS analysis of live cell expression of HLA-ABC, CD80, and CD54 from two different treatments demonstrated that UVADEX completely inactivated Drosophila cells (Figure 3(b), right channel) while the treatment from [gamma]-irradiation did not inactivate Drosophila cells completely (Figure 3(b), middle channel).
In addition, phenotypic characterisation of AMs and IMs in mice revealed differences in the expression levels of MHC classII, CD11b, CD14, CD45, CD54, CD68, CD71, CD204, CD206, and Siglec-F [5-9].
Hooftman-den Otter et al., "Expression of the leucocyte integrin LFA-1 (CD11a/CD18) and its ligand ICAM-1 (CD54) in lymphoid malignancies is related to lineage derivation and stage of differentiation but not to tumor grade," Leukemia, vol.
When incubated with VEGF, the expression of VEGFR1, VEGFR2, von Willebrand factor, and CD54 is increased [104, 105].
Once prepared, the platelet-poor plasma is labeled with fluorescent monoclonal antibodies for staining specific surface antigens expressed on endothelial cells such as CD31 and CD54, and the cytometric analysis is performed by applying forward and side light scatter with calibration beads of a known diameter [58].
Furthermore, they demonstrated that statins reduce the cell surface expression of other immunoregulatory molecules, such as MHC-I, CD3, CD4, CD8, CD28, CD40, CD80, CD86, and CD54 (Kuipers et al).
Vascular cellular adhesion molecule-1 and ICAM1, (also known as CD54) are adhesion molecules of similar structure and function.
Finally, lack of CD29 ([beta]-1 integrin) and CD54 (ICAM-1) in IVLBCL maybe potentially useful diagnostic feature.