CD53

CD53

a type III transmembrane protein present on leukocytes, platelets, osteoblasts, and osteoclasts; contributes to the transduction of CD2-generated signals in T cells and natural killer cells; facilitates cytoplasmic calcium flux in B cells, monocytes, and granulocytes; and plays a role in activation of the monocyte oxidative burst; expressed in hemopoietic neoplasms and myelomas.
References in periodicals archive ?
Total amount excluding benefits for the initial period of the framework agreement (identical amount for each renewal period): minimum eur 40 000 (cd53: eur 40 000 / sdis 53: without minimum), maximum eur 175 000 (cd53: eur 160 000 / sdis53: eur 15 000).
Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis.
Yanai et al., "Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis," Journal of Human Genetics, vol.
CD53 belongs to the tetraspanin family, transmembrane proteins that have multiple functions in, e.g,.
Crowe, "Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and macrophages in HIV-1 infection," Journal of Leukocyte Biology, vol.
Guy, "The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 integrin) and CD53," European Journal of Applied Physiology, vol.
The Effect of intensive moderate and downhill running on human blood lymphocytes expressing the adhesion activation molecules CD54 (Icam -1), CD18, and CD53. European Journal of Applied Physiology, 97(1): 109-121.
However effects on expression of 5 other genes, CDKN2C, FHL1, HGF, IL1RL1, CD53, are associated with tumor growth and carcinogenesis.
In this analysis, the second PC illustrated the link among HINT1, KIAA1712, RHEBL1, FAM40A, CD53, ELOVL4, and CTSS genes, which have a positive relationship with PC2.
This group includes CD63, CD9 and CD53. CD63 is the most important member of this family.
There is also evidence that high intensity exercise inhibits the NK cell-surface expression of several adhesion molecules (CD54, CD18, and CD53), potentially allowing them to migrate from peripheral lymphoid organs into the circulation [8].